Browsing by Subject "Amorphous solid dispersion (ASD)"
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The development of paracetamol and dapsone amorphous solid dispersions
(North-West University (South-Africa), 2021)The development of APIs was focused on the crystalline form over the years, but as the poor solubility of new drugs increased, the focus turned to developing the amorphous form of the drug. Dapsone (DAP) is no exception, ... -
The development of ritonavir and pyrimethamine amorphous solid dispersions
(North-West University (South-Africa), 2021)Poorly soluble drugs are a major problem in the pharmaceutical industry. Not only does it lead to formulation difficulties, but it also leads to poor absorption and poor bioavailability of drugs. Ritonavir (RTV) is a ...