Browsing by Author "Jacobs, Adriaan"
Now showing items 1-6 of 6
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Artificial membranes in combination with selected natural oils for in vitro drug passive diffusion screening in Ussing type chamber apparatus applied to gastro-retentive systems
(Taylor & Francis, 2020)This study aimed at developing an effective in vitro technique for the screening of drug passive diffusion utilising artificial membranes in combination with three selected oils (i.e. cognac, emu, and olive oil). Artificial ... -
The association of PAI-1 with 24 h blood pressure in young healthy adults is influenced by smoking and alcohol use: the African-PREDICT study
(Elsevier, 2020)Background and aims The association between plasminogen activator inhibitor-1 (PAI-1) and blood pressure is well established, but it is debatable whether raised PAI-1 levels precede or result from raised blood pressure. ... -
Associations of plasma total phospholipid fatty acid patterns with feeding practices, growth, and psychomotor development in 6‐month‐old South African infants
(Wiley, 2019)The objective of this study was to assess plasma fatty acid (FA) patterns of 6‐month‐old South African infants and to determine their association with feeding practices, growth, and psychomotor development. Plasma total ... -
Breast milk and erythrocyte fatty acid composition of lactating women residing in a peri‑urban South African township
(Elsevier, 2020)Data on breast milk fatty acid (FA) composition in South African lactating women in relation to their FA status, as well as on potential compositional changes within feed, are limited. The aim of this study was to assess ... -
Plasminogen activator inhibitor-1 activity and the 4G/5G polymorphism are prospectively associated with blood pressure and hypertension status
(Wolters Kluwer, 2019)Objectives: Plasminogen activator inhibitor-1 (PAI-1) has consistently shown positive associations with blood pressure (BP). Whether elevations in PAI-1 levels precede or result from raised BP is still under debate and ... -
Urinary metabolomics, dietary salt intake and blood pressure: the African-PREDICT study
(Springer Nature, 2023)In Black populations excessive salt intake may exacerbate the genetic predisposition to hypertension and promote the early onset of cardiovascular disease. Ethnic differences in the interaction between sodium intake and ...
