Now showing items 1669-1688 of 2707

    • A metabolomics investigation of a nanogold drug vehicle on experimental animals 

      Bartlett, Sonja (North-West University (South Africa), 2019-05)
      Nanotechnology has increasingly received attention the last few decades and the term refers to the categories of applied science and technology, where the combining key subject is the study of matter in scales of 1 to 100 ...
    • A metabolomics investigation of Fibromyalgia Syndrome 

      Malatji, B.G. (North-West University, 2018)
      This thesis, entitled: "A metabolomics investigation of Fibromyalgia Syndrome", deals with Fibromyalgia Syndrome (FMS), a chronic widespread pain disorder with an estimated prevalence of 3.2% in the South African general ...
    • A metabolomics investigation of in utero antiretroviral exposure to neonates 

      Moutloatse, G.P. (North-West University, 2017)
      This thesis, with the title "A metabolomics investigation of in utero antiretroviral exposure to neonates", deals with the concern over adverse metabolic consequences reported for some neonates prenatally exposed to ...
    • A metabolomics investigation of selected m.3243A>G mutation phenotypes 

      Esterhuizen, K. (North-West University, 2018)
      Mitochondrial disease (MD) is a subgroup of inborn errors of metabolism, which can be caused by a mutation in either the nuclear DNA (nDNA) or mitochondrial DNA (mtDNA). One of the most common mtDNA disease causing mutations ...
    • A metabolomics investigation of tuberculous meningitis in infants and children 

      Mason, Shayne William (North-West University (South Africa), 2016)
      This thesis, titled: ‘A metabolomics investigation of Tuberculous Meningitis in infants and children’, deals with tuberculous meningitis (TBM), the most severe complication of tuberculosis (TB) and major pandemic of our ...
    • A metabolomics investigation on experimental interventions of acute alcohol consumption 

      Irwin, C. (North-West University, 2018)
      This thesis, titled: "A metabolomics investigation on experimental interventions of acute alcohol consumption", deals with a current topic of global interest, namely, alcohol use and abuse. Alcohol abuse is associated with ...
    • The metabolomics of acute alcohol abuse 

      Mason, Shayne William (North-West University, 2010)
      Alcohol is a substance used and abused by many individuals. The metabolic perturbations caused by excessive alcohol consumption are widespread throughout the human body. One of the primary consequences of alcohol abuse, ...
    • Metabolomics of bilharziasis 

      Moutloatse, Gontse Panache (North-West University, 2012)
      Bilharziasis, a disease that is a major health problem in tropical and subtropical countries, is caused by worms of the genus Schistosoma. The main disease–causing species are S. haematobium, S. mansoni and S. japonicum. ...
    • Metabolomics of hypertension in South Africans : the SABPA Study 

      Van Deventer, Cynthia Antoinette (North-West University (South Africa), 2015)
      There has been growing concern in recent years about the alarmingly high prevalence and severity of hypertension and other cardiovascular diseases in individuals from newly (or recently) westernised countries such as ...
    • A metabolomics study of selected perturbations of normal human metabolism 

      Davoren, Elmarie (North-West University, 2010)
      Metabolism is an integrated network of biochemical pathways involving a series of enzymecatalysed anabolic or catabolic reactions in cells. Metabolites are chemical compounds that are involved in or are products ...
    • Metagenomic analysis of 16S sequences of nitrifying bacteria and archaea inhabiting maize rhizosphere 

      Ayiti, Oluwatobi Esther (North-West University (South Africa), 2022)
      The global nitrogen cycle has been disrupted, mainly as a result of nitrogen-based synthetic fertilizers and other agrochemicals used in plant cultivation. Microbial inoculation is fast becoming an environmentally friendly ...
    • Metagenomic analysis of agricultural soils under organic and inorganic fertilization 

      Enebe, Matthew Chekwube (North-West University (South Africa), 2021)
      Soil fertilization is an age-old agricultural practice aimed at increasing soil nutrition and soil health. Recently, agriculturists have come to the realization that inorganic fertilizer application over time could result ...
    • Metagenomic analysis of endophytic microbiome inhabiting maize plant 

      Fadiji, Ayomide Emmanuel (North-West University (South Africa), 2021)
      Endophytes are promising microbes which support the plant in many beneficial ways such as growth promotion and health improvement with no harmful effects to their host. However, to have better insights in to important ...
    • Metagenomic analysis of rhizospheric soil microbial communities associated with Striga infested maize field 

      David, Oluchi Glory (North-West University (South Africa), 2023)
      The most problematic weed in sub-Saharan Africa (SSA), often known as witchweed, is an obligate root hemiparasite of grasses that significantly reduces and severely damages food crops. In this study, the structure and ...
    • Metagenomics survey of major metabolic network of sunflower microbiota 

      Alawiye, Temitayo Tosin (North-West University (South Africa), 2021)
      The microbial communities inhabiting the root, termed the rhizosphere, are in a symbiotic association with their host. However, the plant-microbe interaction study at its current stage is still an evolving field of science. ...
    • Metal composition of zooplankton from the Western Indian Ocean 

      Van Aswegen, J.D. (North-West University (South Africa), 2020)
      The Indian Ocean is probably the least researched ocean of the world. It is the third largest ocean and has many unique topographic, geologic, oceanographic, biological, and socio-economic features. The current system is ...
    • Metallic elements in Odonata from South Africa 

      Lesch, Valesia (North-West University (South Africa), Potchefstroom Campus, 2018)
      Adult dragonflies are aerial predatory arthropods that occur globally. However, no research on adult dragonflies as potential indicators of metallic elements in the environment or metallic element concentrations and relative ...
    • Metallic elements in South African sea turtle and crocodile eggs and eggshells 

      Du Preez, M. (North-West University, 2018)
      There are concerns about metal concentrations in aquatic and marine environments due to pollution and subsequent bioaccumulation. Contaminants, such as metals and metalloids enter the water environment from industrial ...
    • Metallothionein expression in tissues of rotenone-treated rats 

      Pretorius, Judey (North-West University, 2006)
      Mitochondrial NADH:ubiquinone oxidoreductase (complex I) carries out a number of well defined functions required for cell physiology. Deficiencies of complex I lead to multi-system disorders that include several well-known ...
    • Metallothionein involvement in mitochondrial function and disease : a metabolomics investigation 

      Lindeque, Jeremie Zander (North-West University, 2011)
      One of the many recorded adaptive responses in respiratory chain complex I deficient cells is the over-expression of the small metal binding proteins, metallothioneins (MTs). The antioxidant properties of MTs putatively ...