Browsing Health Sciences by Subject "Rifampicin"
Now showing items 1-5 of 5
-
The development and evaluation of a novel hybrid PLGA nanoparticle-Pheroid® with the potential to improve tuberculosis therapy
(North-West University, Potchefstroom Campus, 2018)The development of drug delivery technologies has the potential to bring both therapeutic and commercial value to future healthcare products. Drug delivery technologies are transport vehicles that help overcome the ... -
The effect of pharmaceutical excipients on rifampicin release from chitosan beads
(North-West University, 2004)Controlled release systems aim at achieving a predictable and reproducible drug release over a desired time period. These systems allow reduced dosing frequency, constant drug levels in the blood, increased patient compliance ... -
The impact of PheroidTM technology on the bioavailability and efficacy of anti-tuberculosis drugs in an animal model
(North-West University, 2009)Tuberculosis (TB) is a worldwide pandemic with vast challenges in the fight against the disease. Challenges include the long and tedious treatment regimens and chemotherapy with adverse side effects. One approach in ... -
Rifampicin raw materials complexities and approaches to address solubility and in vitro permeability
(North-West University (South-Africa), 2021)Tuberculosis is classified as a global emergency because it is taking lives at an alarming rate and developing countries with insufficient health care systems are primarily affected. Fixed dose combination drugs (FDCs) ... -
Transdermal delivery of isoniazid and rifampicin by pheroid technology
(North-West University, 2007)The aim of this in vitro study was to investigate the feasibility of the transdermal delivery of isoniazid (INH) and rifampicin (RMP) by means of the novel PheroidTM technology system. The application of the latter is ...