Browsing Health Sciences by Author "Aucamp, M.E."
Now showing items 1-5 of 5
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Amorphism and polymorphism of azithromycin
Odendaal, Roelf Willem (North-West University, 2012)Azithromycin, an azalide and member of the macrolide group, is a broad spectrum antimicrobial, representing one of the bestselling antimicrobials worldwide. It is derived from erythromycin and exhibits improved acidic ... -
The detection and quantification of biomolecules in biological sample matrices
Viljoen, Francois Petrus (North-West University (South-Africa), 2019)In the bodies of living humans and animals, endogenous biomolecules, and in particular the chemical messengers, play an essential role in the maintenance and functionality of physiological processes (Daintith, 2008; Gault ... -
The development and validation of HPLC methods for the detection of drug and detergent traces on laboratory glassware in a pharmaceutical laboratory
Mothobi, Pride Mmakeletso (North-West University, 2012)Pharmaceutical contract testing laboratories carry a responsibility to ensure that medicine made available for consumption by patients is of the approved quality for their intended health use. Glassware is an essential ... -
Formulation of an emulgel for topical delivery of roxithromycin
Steenkamp, Vernice (North-West University (South-Africa), 2020)The aim of this study was to establish whether liposomal or niosomal vesicle systems containing roxithromycin could be developed further into semi-solid formulations (emulgels) for topical delivery of the active pharmaceutical ... -
The physico-chemical properties and recrystallisation kinetics of selected amorphous active ingredients
Milne, Marnus (North-West University (South Africa) , Potchefstroom Campus, 2015)During the last two to three decades the application of amorphous solid-state forms within the pharmaceutical industry gained much interest. The rationale for this heightened interest is the increased aqueous solubility, ...