Search
Now showing items 1-10 of 20
Blunted neuro-endocrine responses linking depressive symptoms and ECG left ventricular hypertrophy in black Africans: the SABPA study
(Wolters Kluwer, 2014)
Objective: Chronic psychosocial stress as experienced in an urban environment plays an important role in the aetiology of depression-related cardiovascular risk. It is uncertain whether acute mental stress responses aggravate ...
Procoagulant reactivity to laboratory acute mental stress in Africans and Caucasians, and its relation to depressive symptoms: the SABPA study
(Thieme, 2013)
The risk of cardiovascular disease is dramatically increasing in Africans (black). The prothrombotic stress response contributes to atherothrombotic disease and is modulated by depressive symptoms. We examined coagulation ...
Depression, cardiometabolic function and left ventricular hypertrophy in African men and women: the SABPA study
(Taylor & Francis, 2013)
Depressive symptoms are associated with an increased risk for developing cardiovascular diseases, driven by its link to the metabolic syndrome (MetS). This phenomenon, however, still needs to be investigated in the African ...
Effects of acute and chronic stress on the L-arginine nitric oxide pathway in black and white South Africans: the sympathetic activity and ambulatory blood pressure in Africans study
(Lippincott, Williams & Wilkins, 2013)
OBJECTIVE:
This study investigated the impact of stress on effectors of the L-arginine/nitric oxide (NO) system including the endogenous inhibitor asymmetric dimethylarginine (ADMA).
METHODS:
Black (n = 168) and white ...
Comparison of Telomere Length in Black and White Teachers From South Africa: the Sympathetic Activity and Ambulatory Blood Pressure in Africans Study
(Lippincott Williams & Wilkins, 2015)
Objective: Telomere length is a marker of biological aging that has been linked to cardiovascular disease risk. The black South African population is witnessing a tremendous increase in the prevalence of cardiovascular ...
Cohort profile: sympathetic activity and ambulatory blood pressure in Africans (SABPA) prospective cohort study
(Oxford Univ Press, 2015)
Adapting to an over–demanding stressful urban environment may exhaust the psychophysiological resources to cope with these demands, and lead to sympathetic nervous system dysfunction. The evidence that an urban–dwelling ...
Low serum testosterone and increased diastolic ocular perfusion pressure: a risk for retinal microvasculature
(Verlag Hans Huber Hogrefe Ag, 2015)
Summary:
Background: Low levels of testosterone in men and changes in retinal microvascular calibre are both associated with hypertension and cardiovascular disease risk. Sex hormones are also associated with blood flow ...
Defensive coping and renovascular disease risk. Adrenal fatigue in a cohort of Africans and Caucasians: the SABPA study
(Elsevier, 2015)
Background: Defensive coping is an established cardiovascular risk factor in Africans. Additionally, chronic, excessive or inadequate hypothalamic pituitary adrenal axis (HPAA) stress responses could either increase or ...
Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
(Elsevier, 2015)
Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multi-ethnic sample of ...
Chronic depression symptoms and salivary NOx are associated with retinal vascular dysregulation: the SABPA study
(Elsevier, 2016)
Background
Depression has been associated with impaired nitric oxide (NO)-mediated vasodilation and vascular dysregulation (VD). Whether depression and NO levels will disturb retinal haemodynamics is not clear.
Objectives ...