Browsing Faculty of Health Sciences by Subject "Mitochondria"
Now showing items 1-4 of 4
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A critical role of mitochondria in BDNF-associated synaptic plasticity after one-week vortioxetine treatment
(Oxford Univ Press, 2018)Background Preclinical studies have indicated that antidepressant effect of vortioxetine involves increased synaptic plasticity and promotion of spine maturation. Mitochondria dysfunction may contribute to the pathophysiological ... -
Mitochondria are critical for BDNF-mediated synaptic and vascular plasticity of hippocampus following repeated electroconvulsive seizures
(Oxford Univ Press, 2018)Background Electroconvulsive therapy is a fast-acting and efficient treatment of depression used in the clinic. The underlying mechanism of its therapeutic effect is still unclear. However, recovery of synaptic connections ... -
Mitochondrial DNA replication and OXPHOS gene transcription show varied responsiveness to Rieske protein knockdown in 143B cells
(Elsevier, 2011)Genetic, biochemical and phenotypic diversity is a hallmark of OXPHOS deficiencies. Among the responses frequently reported for these deficiencies is differential expression of several genes involved in mitochondrial ... -
Mitochondrial plasticity of the hippocampus in a genetic rat model of depression after antidepressant treatment
(Wiley, 2013)Depressive disorders and the treatment thereof have been associated with a number of neuroplastic events, such as neurogenesis and synaptic remodeling in discrete areas of the brain. The associations of these events in ...