Browsing Faculty of Health Sciences by Subject "Mathematical model"

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    • A mathematical model of recombinase polymerase amplification under continuously stirred conditions 

      Moody, Clint; Viljoen, Hendrik; Newell, Heather (Elsevier, 2016)
      Growing interest surrounds isothermal PCR techniques which have great potential for miniaturization for mobile diagnostics. Particularly promising, Recombinase Polymerase Amplification (RPA), combines this advantage of ...

    • A model of isoniazid treatment of tuberculosis 

      Lemmer, Yolandy; Grobler, Anne; Viljoen, Hendrik; Moody, Clint (Elsevier, 2014)
      A mathematical model is presented of the growth and death of bacilli in a granuloma. The granuloma is treated with isoniazid (INH), a drug that inhibits the synthesis of mycolic acids (MA). Since MA is an essential component ...