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The monoamine oxidase inhibition properties of selected structural analogues of methylene blue
(Elsevier, 2017)
The thionine dye, methylene blue (MB), is a potent inhibitor of monoamine oxidase (MAO) A, a property that may, at least in part, mediate its antidepressant effects in humans and animals. The central inhibition of MAO-A ...
Inhibition of c-steel corrosion by green tea extract in hydrochloric solution
(ESG, 2017)
Inhibition ability of green tea extract (GTE) on the C38 steel (CS) in 1.0 M HCl was evaluated using different methods such as: weight loss, electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization ...
Ipsilateral corticomotor responses are confined to the homologous muscle following cross-education of muscular strength
(Canadian Science Publishing, 2018)
Cross-education of strength occurs when strength-training 1 limb increases the strength of the untrained limb and is restricted to the untrained homologous muscle. Cortical circuits located ipsilateral to the trained limb ...
Synthesis and in vitro evaluation of 2-heteroarylidene-1-tetralone derivatives as monoamine oxidase inhibitors
(Thieme, 2018)
The present study investigates the human monoamine oxidase (MAO) inhibition properties of a series of twelve 2-heteroarylidene-1-tetralone derivatives. Also included are related cyclohexylmethylidene, cyclopentylmethylidene ...
Monoamine oxidase inhibition by selected dye compounds
(Wiley, 2019)
Monoamine oxidase (MAO) is an important drug target as the MAO isoforms play key roles in neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease, as well as in neuropsychiatric diseases such as ...
The evaluation of 1-tetralone and 4-chromanone derivatives as inhibitors of monoamine oxidase
(Springer, 2020)
Monoamine oxidase (MAO) is of much clinical relevance, and inhibitors of this enzyme are used in the treatment for neuropsychiatric and neurodegenerative disorders such as depression and Parkinson’s disease. The present ...
Monoamine oxidase inhibition properties of 2,1‑benzisoxazole derivatives
(Springer, 2023)
onoamine oxidase (MAO) are favoenzymes that metabolize neurotransmitter, dietary and xenobiotic amines to their corre sponding aldehydes with the production of hydrogen peroxide. Two isoforms, MAO-A and MAO-B, are expressed ...
Monoamine oxidase inhibition by Kavalactones from Kava (Piper Methysticum)
(Thieme, 2019)
Monoamine oxidases (MAOs) are key metabolic enzymes for neurotransmitter and dietary amines and are targets for the treatment of neuropsychiatric and neurodegenerative disorders. This study examined the MAO inhibition ...
Optimization of pyrrolo[3,4‐f]indole‐5,7‐dione and indole‐5,6‐dicarbonitrile derivatives as inhibitors of monoamine oxidase
(Wiley, 2019)
In recent studies, we have investigated the monoamine oxidase (MAO) inhibition properties of pyrrolo[3,4‐f]indole‐5,7‐dione and indole‐5,6‐dicarbonitrile derivatives. Since numerous high potency MAO inhibitors are present ...
1,3,4-Oxadiazol-2-ylbenzenesulfonamides as privileged structures for the inhibition of monoamine oxidase B
(Elsevier, 2019)
The present study investigates the monoamine oxidase (MAO) inhibition properties of a series of ten 5-aryl-1,3,4-oxadiazol-2-ylbenzenesulfonamides. The target compounds were synthesized by dehydration of the corresponding ...