Search
Now showing items 1-8 of 8
Inhibition of monoamine oxidase by 8-phenoxymethylcaffeine derivatives
(Elsevier, 2012)
A recent study has reported that a series of 8-benzyloxycaffeines are potent and reversible inhibitors of both human monoamine oxidase (MAO) isoforms, MAO-A and -B. In an attempt to discover additional caffeine derivatives ...
Inhibition of monoamine oxidase by selected C6-substituted chromone derivatives
(Elsevier, 2012)
Chromone has been reported to be a useful scaffold for the design of monoamine oxidase (MAO) inhibitors. In an attempt to discover highly potent MAO inhibitors and to contribute to the known structureeactivity relationships ...
Monoamine oxidase inhibition by C4-substituted phthalonitriles
(Elsevier, 2012)
It was recently reported that a series of C5-substituted phthalimides are remarkably potent reversible inhibitors of recombinant human monoamine oxidase (MAO) B. Modeling studies suggested that the phthalimide ring forms ...
Inhibition of monoamine oxidase by selected C5- and C6-substituted isatin analogues
(Elsevier, 2011)
Previous studies have shown that (E)-5-styrylisatin and (E)-6-styrylisatin are reversible inhibitors of human monoamine oxidase (MAO) A and B. Both homologues are reported to exhibit selective binding to the MAO-B isoform ...
Inhibition of monoamine oxidase by C5-substituted phthalimide analogues
(Elsevier, 2011)
Literature reports that isatin as well as C5- and C6-substituted isatin analogues are reversible inhibitors
of human monoamine oxidase (MAO) A and B. In general, C5- and C6-substitution of isatin leads to enhanced binding ...
Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues
(Elsevier, 2010)
Based on recent reports that several (E)-8-styrylcaffeinyl analogues are potent reversible inhibitors of
monoamine oxidase B (MAO-B), a series of 8-benzyloxycaffeinyl analogues were synthesized and evaluated
as inhibitors ...
8-Aryl- and alkyloxycaffeine analogues as inhibitors of monoamine oxidase
(Elsevier, 2011)
Recently it was reported that a series of 8-benzyloxycaffeine analogues are potent reversible inhibitors of human monoamine oxidase (MAO) A and B. In an attempt to discover additional C8 oxy substituents of caffeine that ...
Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues
(Elsevier, 2010)
Based on recent reports that several (E)-8-styrylcaffeinyl analogues are potent reversible inhibitors of monoamine oxidase B (MAO-B), a series of 8-benzyloxycaffeinyl analogues were synthesized and evaluated as inhibitors ...