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Concurrent class analysis identifies discriminatory variables from metabolomics data on isovaleric acidemia
(Springer, 2012)
Metabolomics data are typically complex and high dimensional. Multivariate dimension-reducing techniques have thus been developed for analysing metabolomics data to disclose underlying relationships, with principal component ...
Disclosure of a putative biosignature for respiratory chain disorders through a metabolomics approach
(Springer, 2013)
The diagnosis of respiratory chain deficiencies
(RCDs) is complicated and the need for a diagnostic biomarker
or biosignature has been widely expressed. In this
study, the metabolic profile of a selected group of 29 ...
Metabolomics of urinary organic acids in respiratory chain deficiencies in children
(Springer, 2012)
Metabolomic analysis of the urinary organic
acids from 39 selected children with defined respiratory
chain deficiencies (RCDs) was performed using untargeted
gas chromatography–mass spectrometry, revealing the
presence ...