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Nocturnal blood pressure, 3-methoxy-4-hydroxyphenylglycol and carotidIntima-media thickness: the SABPA Study
(Elsevier, 2013)
Background: Research demonstrated a significant relationship between elevated nocturnal blood pressure and sym-pathetic hyperactivity. The study aimed to investigate possible associations between norepinephrine ...
Effects of acute and chronic stress on the L-arginine nitric oxide pathway in black and white South Africans: the sympathetic activity and ambulatory blood pressure in Africans study
(Lippincott, Williams & Wilkins, 2013)
OBJECTIVE:
This study investigated the impact of stress on effectors of the L-arginine/nitric oxide (NO) system including the endogenous inhibitor asymmetric dimethylarginine (ADMA).
METHODS:
Black (n = 168) and white ...
Nocturnal blood pressure, 3–methoxy–4–hydroxyphenylglycol and carotid intima–media thickness: the SABPA study
(Elsevier, 2013)
Background: Research demonstrated a significant relationship between elevated nocturnal blood pressure and sym-pathetic hyperactivity. The study aimed to investigate possible associations between norepinephrine ...
Baroreceptor sensitivity, cardiovascular responses and ECG left ventricular hypertrophy in men: the SABPA study
(Taylor & Francis, 2011)
Aim. Research has shown a significant relationship between hypertension and attenuated baroreceptor sensitivity (BRS), which in turn reflects alterations of autonomic control of the cardiovascular system. The objective of ...
Differences in MetS marker prevalence between black African and Caucasian teachers from the North West Province: Sympathetic activity and ambulatory blood pressure in Africans (SABPA) study
(Medpharm, 2011)
Background: The aim of this study was to compare metabolic syndrome (MetS) prevalence between black and Caucasian Africans using different definitions, and secondly, to determine the association between MetS, anthropometric ...
Associations of cholesterol and glucose with cardiovascular dysfunction in black Africans: the SABPA study
(Informa healthcare, 2011)
The aim was to determine whether blood glucose or cholesterol is the more prominent contributor to cardiovascular dysfunction in 101 African men and 99 African women. We measured ambulatory daytime blood pressure (BP), ...
Using MutPred derived mtDNA load scores to evaluate mtDNA variation in hypertension and diabetes in a two-population cohort: the SABPA study
(Elsevier, 2017)
Mitochondrial DNA (mtDNA) variation has been implicated in many common complex diseases, but inconsistent and contradicting results are common. Here we introduce a novel mutational load hypothesis, which also considers the ...
Implementing a new variant load model to investigate the role of mtDNA in oxidative stress and inflammation in a bi-ethnic cohort: the SABPA study
(Taylor & Francis, 2019)
Mitochondrial DNA (mtDNA) variation has been implicated in several common complex and degenerative diseases, including cardiovascular disease. Inflammation is seen as part of many of these conditions. Mitochondria feature ...
Defensive coping and essential amino acid markers as possible predictors for structural vascular disease in an African and Caucasian male cohort: the SABPA study
(Wiley, 2017)
Defensive coping (DefS), oxidative stress, inflammation, and related amino acids (phenylalanine [Phe] and tyrosine [Tyr]) have been implicated in cardiovascular disease. This study assessed whether inflammation, oxidative ...
Determining cut-off values for neck circumference as a measure of the metabolic syndrome amongst a South African cohort: the SABPA study
(Springer-Science, 2012)
The aim was to determine receiver operating characteristic (ROC) neck circumference (NC) cut offs best associated with the metabolic syndrome (MetS) in a South African cohort. We included 409 urban Africans and Caucasians ...