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A challenged sympathetic system is associated with retinal vascular calibre in a black male cohort: the SABPA Study
(Intech, 2016)
Sympathetic system hyperactivity and depression are related to cardiac remodelling in Black men. We investigated whether sympathetic system hyperactivity and depressive symptoms are related to retinal vascular dysregulation. ...
The protective role of oestradiol against silent myocardial ischemia and hypertension risk in South African men: the SABPA study
(Elsevier, 2017)
"Background: Oestradiol has a protective effect on coronary artery health in women but the effect it has on men, is controversial. A translational approach was followed to assess whether sex hormone levels are associated ...
Three-year changes of prothrombotic factors in Africans with a high clinical suspicion of obstructive sleep apnea
(Schattauer Publishers, 2016)
A hypercoagulable state might be one important mechanism linking obstructive sleep apnea (OSA) with incident myocardial infarction and stroke. However, previous studies on prothrombotic factors in OSA are not uniform and ...
Ethnic disparity in defensive coping endothelial responses: the SABPA study
(Elsevier, 2015)
Objectives:
Defensive coping (DefS) in Blacks has been associated with greater cardiovascular risk than in their White counterparts. We examined associations between endothelial function mental stress responses and markers ...
Procoagulant reactivity to laboratory acute mental stress in Africans and Caucasians, and its relation to depressive symptoms: the SABPA study
(Thieme, 2013)
The risk of cardiovascular disease is dramatically increasing in Africans (black). The prothrombotic stress response contributes to atherothrombotic disease and is modulated by depressive symptoms. We examined coagulation ...
Low serum testosterone and increased diastolic ocular perfusion pressure: a risk for retinal microvasculature
(Verlag Hans Huber Hogrefe Ag, 2015)
Summary:
Background: Low levels of testosterone in men and changes in retinal microvascular calibre are both associated with hypertension and cardiovascular disease risk. Sex hormones are also associated with blood flow ...
Chronic depression symptoms and salivary NOx are associated with retinal vascular dysregulation: the SABPA study
(Elsevier, 2016)
Background
Depression has been associated with impaired nitric oxide (NO)-mediated vasodilation and vascular dysregulation (VD). Whether depression and NO levels will disturb retinal haemodynamics is not clear.
Objectives ...
BDNF increases associated with constant troponin T levels and may protect against poor cognitive interference control: the SABPA prospective study
(Wiley, 2019)
Background: Brain‐derived neurotrophic factor (BDNF) modulates brain health and cognition, which can interfere with executive cognitive function. BDNF was impli-cated with microcirculatory ischaemia and may reflect ...
Heart rate variability, the dynamic nature of the retinal microvasculature and cardiac stress: providing insight into the brain-retina-heart link: the SABPA study + Correction
(Nature, 2020)
Background and aims
Decreased heart-rate-variability (HRV) indicates increased sympathetic nervous system (SNS) activity and modulation with a shift in the sympatho-vagal balance towards SNS predominance. Increased SNS ...
Retinal vasculature reactivity during flicker light provocation, cardiac stress and stroke risk in Africans: the SABPA study
(Springer, 2019)
Structural and functional similarities exist between the retinal, cerebral and, as previously suggested, the coronary microvasculature. Retinal microvascular structure and functionality (in response to flicker-light-indu ...