Browsing Research Output by Subject "Clearance"
Now showing items 1-2 of 2
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The effect of the Pheroid delivery system on the in vitro metabolism and in vivo pharmacokinetics of artemisone
(Taylor & Francis, 2014)Objectives: The objectives were to determine the pharmacokinetics (PK) of artemisone and artemisone formulated in the Pheroid® drug delivery system in primates and to establish whether the formulation affects the in vitro ... -
Influence of CYP2B6 516G>T polymorphism and interoccasion variability (IOV) on the population pharmacokinetics of efavirenz in HIV-infected South African children
(Springer, 2012)Objective To investigate the influence of CYP2B6 516G>T polymorphism, as a covariate, and of interoccasion variability (IOV) on the oral clearance (CL/F) of efavirenz (EFV) in treatment-naïve black South African children ...