Browsing by Subject "Sequence-independent genome amplification"
Now showing items 1-2 of 2
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Investigating the importance of co-expressed rotavirus proteins in the development of a selection-free rotavirus reverse genetics system
(2014)Reverse genetics is an innovative molecular biology tool that enables the manipulation of viral genomes at the cDNA level in order to generate particular mutants or artificial viruses. The reverse genetics system for the ... -
Whole genome characterisation and engineering of chimaeric rotavirus–like particles using African rotavirus field strains
(North-West University, 2012)Despite the global licensure of two live-attenuated rotavirus vaccines, Rotarix® and RotaTeq®, rotavirus remains the major cause of severe dehydrating diarrhoea in young mammals and the need for further development of ...