Browsing by Subject "Reactive oxygen species (ROS)"
Now showing items 1-5 of 5
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Analysis of metallothionein gene expression in oxidative stress related disorders
(North-West University, 2004)Increased reactive oxygen species (ROS) have been reported to be at the centre of various diseases. Although several reports have implicated elevated levels of ROS in the pathogenesis of diabetes mellitus, the early ... -
The antimicrobial peptide nisin Z induces selective toxicity and apoptotic cell death in cultured melanoma cells
(Elsevier, 2018)Reprogramming of cellular metabolism is now considered one of the hallmarks of cancer. Most malignant cells Reprogramming of cellular metabolism is now considered one of the hallmarks of cancer. Most malignant cells present ... -
An in vitro evaluation of the antibacterial and anticancer properties of the antimicrobial peptide nisin Z
(North-West University (South Africa), Potchefstroom Campus, 2018)The rise in antibiotic resistance and the lack of the development of new antibiotics poses a considerable threat to human health. This is especially of concern in individuals who are immune-compromised (due to immunosuppressive ... -
The metabolic profile of phenylbutyric acid and its antioxidant capacity in vervet monkeys
(North-West University, 2010)X–linked adrenoleukodystrophy (X–ALD) is the most common peroxisomal enzyme deficiency disorder, characterized by inborn mutations in the ABCD1 gene, an ATP–binding cassette (ABC) half–transporter. The ABCD1 gene encodes ... -
Preparation, stability and in vitro evaluation of liposomes containing chloroquine
(North-West University, 2010)Malaria is currently a huge treat worldwide, as far as infections are concerned, and is responsible for thousands of deaths per annum. The dilemma associated with the development of anti–malarial drug resistance over the ...