Browsing by Subject "Reactive oxygen species"
Now showing items 1-10 of 16
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8-Oxo-7,8-dihydro-2’-deoxyguanosine, reactive oxygen species and ambulatory blood pressure in African and Caucasian men: the SABPA study
(Taylor & Francis, 2014)Various studies indicate a relationship between increased oxidative stress and hypertension, resulting in increased DNA damage and consequent excretion of 8-oxo-7,8-dihydro-2’-deoxyguanosine (8-oxodG). The aim of this study ... -
Artemisone and artemiside are potent panreactive antimalarial agents that also synergize redox imbalance in Plasmodium falciparum transmissible gametocyte stages
(American Society for Microbiology, 2018)The emergence of resistance toward artemisinin combination therapies (ACTs) by the malaria parasite Plasmodium falciparum has the potential to severely compromise malaria control. Therefore, the development of new artemisinins ... -
The association of endothelin-1 with markers of oxidative stress in a biethnic South African cohort: the SABPA study
(Springer Nature, 2017)Both endothelin-1 and oxidative stress have important roles in the development of cardiovascular diseases such as hypertension and atherosclerosis. Limited information is available on the interaction between oxidative ... -
Associations between reactive oxygen species, blood pressure and arterial stiffness in black South Africans: the SABPA study
(Springer Nature, 2012)Many mechanisms, including oxidative stress, contribute to hypertension. This study investigated the possible associations between oxidative stress, blood pressure and arterial stiffness in black South Africans. Ambulatory ... -
Cardiovascular reactivity and oxidative stress in young and older adults: the African-PREDICT and SABPA studies
(Taylor & Francis, 2019)Background: Oxidative stress and increased cardiovascular reactivity are associated with endothelial dysfunction and cardiovascular disease development. These factors along with early vascular compromise are more pronounced ... -
The Effect of Metallothionein Overexpression on Inflammation Associated with Mitochondrial Complex I Deficiency
(North-West University (South Africa)North-West University, 2020)Mitochondria form an integral part of the immune system because complex I (CI) of the mitochondrial oxidative phosphorylation system has been identified as a key regulator of the inflammatory response. CI activity suppresses ... -
The effects of radiolabelled agents used in the diagnosis and treatment of cancer, on inflammatory cytokines
(North-West University (South Africa), 2020)This study was conducted to determine the effects that two radiolabelled compounds have on the inflammatory cytokines and oxidative stress biomarkers in xenograft Rowett nude (RNU) rat models. Safety and efficacy are of ... -
Evaluating the effects of fungicides for the control of Exserohilum turcicum on sorghum in South Africa
(North-West University (South Africa), Potchefstroom Campus, 2017)Sorghum (Sorghum bicolor (L.) Moench) is one of the five most widely cultivated grasses in Sub- Saharan Africa. Exserohilum turcicum (Pass.) Leonard and Suggs is a fungal foliar pathogen that causes leaf blight (LB) on ... -
Flow cytometric analysis of the oxidative status in human peripheral blood mononuclear cells of workers exposed to welding fumes
(Taylor & Francis, 2010)Flow cytometry is a simple analytical technique that identifies, counts, and characterizes cells. The oxidative status of cells is influenced by many exogenous sources, such as occupational exposure to welding fumes. This ... -
In vitro evaluation of the cytotoxic and apoptogenic properties of aloe whole leaf and gel materials
(Taylor & Francis, 2014)Aloe gel and whole-leaf materials have shown biological effects with potential therapeutic applications, and recently, their drug-absorption enhancement properties have been discovered. It is important to establish a ...