Browsing by Subject "Quinolone"
Now showing items 1-3 of 3
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Recent progress in the development of anti-malarial quinolones
(BioMed Central, 2014)Available anti-malarial tools have over the ten-year period prior to 2012 dramatically reduced the number of fatalities due to malaria from one million to less than six-hundred and thirty thousand. Although fewer people ... -
Straightforward conversion of decoquinate into inexpensive tractable new derivatives with significant antimalarial activities
(Elsevier, 2016)As part of a programme aimed at identifying rational new triple drug combinations for treatment of malaria, tuberculosis and toxoplasmosis, we have selected quinolones as one component, given that selected examples exhibit ... -
Synthesis and in vitro anti-tubercular evaluation of 6-nitroquinolone-3-carboxamides
(North-West University (South Africa), 2020)Tuberculosis (TB) is a disease that has been a major scourge of humankind since time immemorial. It is an airborne disease that mainly affects the lungs and it is caused by Mycobacterium tuberculosis (Mtb)─ a pathogenic ...