Browsing by Subject "Plasminogen activator inhibitor-1"
Now showing items 1-5 of 5
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The association of uric acid and plasminogen activator inhibitor-1 (PAI-1) with cardiovascular function in South African women : the POWIRS-study
(North-West University, 2006)Motivation: Hypertension is a fast growing health risk, leading to increased incidences of cardiovascular dysfunction and mortality. However, the prevalence of hypertension is higher in some ethnic populations than others. ... -
Endothelial function and vascular health of black South Africans : the significance of plasminogen activator inhibitor-1
(North-West University (South-Africa), 2021)Background and motivation - Plasminogen activator inhibitor-1 (PAI-1), a serine protease inhibitor known for its classic role in fibrinolysis, has in recent years gained attention for its association with impaired vascular ... -
Haemostatic markers and cardiovascular function in black and white South Africans : the SABPA study
(2015)Motivation - In the black population of South Africa, cardiovascular disease (CVD) is rapidly increasing due to urbanisation. Stroke is usually accompanied by a pro-thrombotic haemostatic profile. Changing lifestyle factors ... -
Plasminogen activator inhibitor-1 in black South Africans, methodological and clinical considerations
(North-West University (South Africa) , Potchefstroom Campus, 2016)Introduction and aim Black South Africans are experiencing an increase in the prevalence of cardiovascular disease (CVD). Obesity and abnormal haemostasis are among the underlying risk factors associated with CVD ... -
The contribution of different adipose tissue depots to plasmaplasminogen activator inhibitor-1 (PAI-1) levels
(Elsevier, 2016)Increased plasma plasminogen activator inhibitor-1 (PAI-1) level is considered a mechanistic pathway through which obesity contributes to increased cardiovascular disease risk. Abdominal adipose tissue specifically, is a ...