Browsing by Subject "Permeability"
Now showing items 1-10 of 15
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Amorphism and polymorphism of azithromycin
(North-West University, 2012)Azithromycin, an azalide and member of the macrolide group, is a broad spectrum antimicrobial, representing one of the bestselling antimicrobials worldwide. It is derived from erythromycin and exhibits improved acidic ... -
Breaching the skin barrier through temperature modulations
(Elsevier, 2015)The impermeability of the stratum corneum often hinders the transport of molecules across the skin. Temperature modulations in the skin and the application of local heat both have the potential of circumventing this problem ... -
The effect of feed water TDS on RO membrane rejection rates and performance
(North-West University (South Africa)., 2023)Power generation is a major user of fresh water, which is becoming important for Eskom and South Africa due to the water-scarce status. Therefore, the water usage at a thermal power station is a key metric and reverse ... -
Enhancing the solubility and in vitro permeability of pyrimethamine
(North-West University (South-Africa), 2021)ABSTRACT Malaria poses a substantial health problem, with nearly half of the world’s population susceptible to it. Malaria causes an estimated one million deaths per year. People who fall prey to malaria are also burdened ... -
The identification and application of a method to test chloride ingress into concrete, sulphur-concrete and sulphur-cement coated concrete
(North-West University (South Africa) , Potchefstroom Campus, 2017)Concrete is the main material used for the construction of civil structures in industry. Concrete is also used in the construction of nuclear power plant civil structures (e.g. the containment building). Concrete ages but ... -
Improvement of the pharmaceutical availability and membrane permeability of furosemide by formulation design
(North-West University (South-Africa), 2021)Furosemide is a well-known loop diuretic having weak acidic chemical properties. Furosemide belongs to the Biopharmaceutical Classification System (BCS) class IV because it has poor aqueous solubility and poor membrane ... -
The influence of buffer composition on the solubility of baclofen and sulfadoxine
(North-West University (South-Africa), 2022)The drug discovery process has developed immensely during the last couple of decades. The Biopharmaceutical Classification System (BCS) is a drug development tool that is based on correlation of solubility and membrane ... -
The influence of pH on the in vitro permeation of rhodium through human skin
(Sage, 2017)Workers in precious metals refineries are at risk of exposure to salt compounds of the platinum group metals through inhalation, as well as through the skin. Rhodium salt permeation through the skin has previously been ... -
Investigation of solubility and permeability of sulfadoxine and pyrimethamine mixtures
(North-West University (South Africa) , Potchefstroom Campus, 2017)Sulfadoxine and pyrimethamine are commercially available in a fixed dose combination (FDC) product, which is used as prophylaxis against malaria. These drugs are still on the World Health Organization’s (WHO) essential ... -
Mathematical methodology and software package for investigation of nonstationary hydrogen permeability in membranes used in electrolysers and hydrogen fuel cells
(Elsevier, 2017)As part of the methodology to control gas permeability of functional materials, mathematical approach is considered that takes into account a diffusion process through a plate with the boundary conditions of the 1st and ...