Browsing by Subject "Monoamine oxidase (MAO)"
Now showing items 1-6 of 6
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The antioxidant properties, cytotoxicity and monoamine oxidase inhibition abilities of the crude dichloromethane extract of Tarchonanthus camphoratus L. leaves
(Academic Journals, 2011)Tarchonanthus camphoratus (camphor bush) has been widely used for numerous medicinal purposes. The aim of the present study was to evaluate the antioxidant properties, cytotoxicity and monoamine oxidase inhibition activities ... -
Inhibition of monoamine oxidase by indole and benzofuran derivatives
(Elsevier, 2010)Monoamine oxidase (MAO) is an important drug target for the treatment of neurological disorders. A series of indole and benzofuran derivatives were synthesised and evaluated as inhibitors of the two MAO isoforms, MAO-A and ... -
An investigation of indanone derivatives as inhibitors of monoamine oxidase
(North-West University (South Africa), Potchefstroom Campus, 2018)MAO-A and MAO-B are two isoforms of mitochondrial monoamine oxidase (MAO) that are responsible for the deamination of various monoamine substrates. For example tyramine and dopamine are metabolised by both MAO isoforms. ... -
Monoamine oxidase inhibitory activities of heterocyclic chalcones
(Elsevier, 2015)Studies have shown that natural and synthetic chalcones (1,3-diphenyl-2-propen-1-ones) possess monoamine oxidase (MAO) inhibition activities. Of particular importance to the present study is a report that a series of ... -
The synthesis and evaluation of benzosuberone derivatives as inhibitors of monoamine oxidase
(North-West University, Potchefstroom Campus, 2018)Monoamine oxidase (MAO) is responsible for the catabolism of neurotransmitters such as serotonin and dopamine in the central nervous system and peripheral tissues. MAO inhibitors such as selegiline play a vital part in the ... -
Synthesis and evaluation of sesamol derivatives as inhibitors of monoamine oxidase
(2014)Parkinson’s disease is an age-related neurodegenerative disorder. The major symptoms of Parkinson’s disease are closely linked to the pathology of the disease. The main pathology of Parkinson’s disease consists of the ...