Browsing by Subject "Hyperglycaemia"
Now showing items 1-6 of 6
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Cardiac stress and cardiovascular risk markers : the SABPA study
(North-West University (South-Africa), 2019)Motivation - Pathological cardiac remodelling is a manifestation of end-organ damage and can be characterised by myocyte death and myocyte hypertrophy. An increased hemodynamic burden may follow the cardiac remodelling ... -
Ets-insulin-bolus calculation promotes tighter blycaemic control for type 1 diabetics
(North-West University, 2007)Type 1 Diabetes is a dangerous and life-long disease for which its prevalence is global. Research has shown that tight glycaemic control of this disease significantly reduces the risks of developing several life threatening ... -
Glycaemic control improves fibrin network characteristics in type 2 diabetes: a purified fibrinogen model
(Thieme, 2008)Diabetic subjects have been shown to have altered fibrin network structures.One proposed mechanism for this is non-enzymatic glycation of fibrinogen due to high blood glucose.We investigated whether glycaemic control would ... -
Integrative model of lifestyle effects on cancer via the HbA1c biomarker
(2014)Background: Cancer and diabetes are the second and twelfth leading global causes of death, respectively. Cancer incidence is increased in diabetics compared to non-diabetics. Common pathobiological pathways are shared by ... -
Investigation of the involvement of mitochondrial DNA variants in cardiometabolic disease : the SABPA study
(North-West University (South Africa), Potchefstroom Campus, 2017)Mitochondria are intricately involved in cell homeostatic and adaptive stress signalling pathways, and play a central role in cell differentiation, proliferation and death. Consequently, mitochondrial dysfunction has been ... -
Prospective associations between cardiac stress, glucose dysregulation and executive cognitive function in Black men: the Sympathetic activity and ambulatory blood pressure in Africans study
(Sage, 2018)Objective: Glucose dysregulation is an independent risk factor for cardiovascular and neurodegenerative disease development through synaptic dysfunction resulting in cognitive decline. The aim of this study was to study ...