Browsing by Subject "Cytokines"
Now showing items 1-5 of 5
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Bio-behavioural evaluation of efavirenz and Δ9-tetrahydrocannabinol alone and in combination in rats with respect to psychosis and anxiety
(North-West University (South-Africa), 2019)The highly active antiretroviral therapy, efavirenz (EFV), has been noted to occur as a constituent of a potent new designer drug cocktail called “Nyaope” or “Whoonga”, which is reported to have mind-altering and addictive-like ... -
Characterising the immunometabolic profile of HIV/TB co-infection
(North-West University (South Africa), 2022)The synergy between the human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB) during co-infection of a host is well established. While this synergy is driven ... -
The effects of radiolabelled agents used in the diagnosis and treatment of cancer, on inflammatory cytokines
(North-West University (South Africa), 2020)This study was conducted to determine the effects that two radiolabelled compounds have on the inflammatory cytokines and oxidative stress biomarkers in xenograft Rowett nude (RNU) rat models. Safety and efficacy are of ... -
Probiotic treatment protects against the pro-depressant-like effect of high-fat diet in Flinders Sensitive Line rats
(Elsevier, 2017)Major depressive disorder (MDD) is highly associated with dysmetabolic conditions, such as obesity and diabetes mellitus type 2, and the gut microbiota may interact with both disease entities. We have previously shown that ... -
Probiotic treatment reduces depressive-like behaviour in rats independently of diet
(Elsevier, 2017)The gut microbiota has recently emerged as an important regulator of brain physiology and behaviour in animals, and ingestion of certain bacteria (probiotics) therefore appear to be a potential treatment for major depressive ...