Browsing by Subject "Carbamate"
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Design and synthesis of dual acting carbamate inhibitors of acetylcholinesterase and monoamine oxidase
(North-West University (South Africa) , Potchefstroom Campus, 2017)Alzheimer’s disease (AD), the most common neurodegenerative disorder, affects about 10% of the population over the age of 65 years. The disease is typified by symptoms such as memory loss and impairment in abilities including ... -
Synthesis and transdermal permeation of novel N4-methoxypoly(ethylene glycol) carbamates of cytarabine
(Taylor & Francis, 2010)Background: Cytarabine is a deoxycytidine analogue commonly used in the treatment of hematological malignant diseases. Its clinical utility, however, is severely limited by its short plasma half-life because of the catabolic ...