Browsing by Subject "Acyclovir"
Now showing items 1-8 of 8
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1H NMR spectral identification of medication in cerebrospinal fluid of pediatric meningitis
(Elsevier, 2017)Exploratory metabolomics studies of cerebrospinal fluid (CSF), using proton nuclear magnetic resonance (1H NMR) spectroscopy, hold major potential application in neurodiagnostics. Such studies, however, rely upon established ... -
A comparative study of lamellar gel phase systems and emzaloids as transdermal drug delivery systems for acyclovir and methotrexate
(North-West University, 2004)The skin forms an attractive and accessible route for systemic delivery of drugs as alternative to other methods of administration, such as the oral and parental methods because of the problems associated with last ... -
The effect of Brij 97 and carrageenan on the transdermal delivery of acyclovir
(North-West University, 2006)The skin, by weight, is the largest organ of the body. Human skin serves to provide several important functions that may be classified. in a general context, as protective, maintaining homeostasis and sensing. The outermost ... -
Formulation and evaluation of selected transmucosal dosage forms containing a double fixed-dose of acyclovir and ketoconazole
(Elsevier, 2018)Viral and fungal dermatological manifestations are often the first and only sign of HIV/AIDS. They are cosmetically disfiguring and threaten the quality of life, but can be treated by acyclovir and ketoconazole, correspondingly. ... -
Formulation, in vitro release and transdermal diffusion of acyclovir and ketoconazole for skin conditions in HIV/AIDS patients
(North-West University, 2009)The aim of this in vitro study was to investigate the efficacy of the novel Pheroid™ technology system in a semi-solid dosage form, for the topical delivery of acyclovir (5% w/w), an anti-viral agent and ketoconazole (2% ... -
Topical delivery of different ketoconazole and acyclovir formulations
(North-West University, 2012)Acquired immunodeficiency syndrome (AIDS) has shown a rapid increase in incidence over the past 25 years. Many clinical manifestations occur in patients infected with human immunodeficiency virus (HIV) due to compromised ... -
Transdermal delivery of Acyclovir and Ketoconazole by PheroidTM technology
(North-West University, 2007)The aim of this study was to investigate in vitro transdermal delivery of the antiviral drug, acyclovir and the antifungal drug, ketoconazole, with the aid of the novel Pheroid™ drug delivery system. Since its appearance ... -
Transdermal penetration of acyclovir in the presence and absence of terpenes
(North-West University, 2003)Acyclovir is an antiviral drug used in the treatment and prevention of herpes simplex and varicella-zoster viral infections. The major problem in the transdermal delivery of acyclovir is the permeation in sufficient amounts ...