Browsing by Subject "Absorption enhancers"
Now showing items 1-5 of 5
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Gastrointestinal region specific insulin absorption enhancement by Aloe vera leaf materials
(North-West University (South Africa) , Potchefstroom Campus, 2015)The oral administration route is still the most popular and preferred route for drug administration, but is, however, not suitable for protein and peptide drugs such as insulin, due to their poor bioavailability when ... -
In vitro evaluation of the toxicity profile of N-trimethyl chitosan chloride
(North-West University (South-Africa), 2000)The pharmaceutical scientist 1s confronted by numerous challenges in the area of developing new and effective delivery systems for new classes of drugs such as peptide and protein drugs. Due to the size and polarity ... -
Nasal delivery of insulin with Pheroid technology
(North-West University, 2006)Approximately 350 million people worldwide suffer from diabetes mellitus (DM) and this number increases yearly. Since the discovery and clinical application of insulin in 1921, subcutaneous injections have been the standard ... -
Novel non-invasive protein and peptide drug delivery approaches
(Bentham Science, 2014)Protein and peptide based therapeutics are typically administered by injection due to their poor uptake when administered via enteral routes of drug administration. Unfortunately, chronic administration of these drugs ... -
Preparation and evaluation of multiple-unit solid oral dosage forms containing chemical permeation enhancing agents
(2014)The most popular and convenient route of drug administration remains the oral route, however, protein and peptide drugs such as insulin have poor membrane permeability and stability in the gastrointestinal tract. Absorption ...