Browsing by Author "Tacke, Sabine"
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Comparison of physiological parameters and anaesthesia specific observations during isoflurane, ketamine-xylazine or medetomidine-midazolam-fentanyl anaesthesia in male guinea pigs
Schmitz, Sabrina; Guth, Brian; Tacke, Sabine; Henke, Julia (Public Library of Science, 2016)Guinea pigs (GPs) are difficult to anaesthetize successfully, the choices for anaesthesia are limited and physiological parameters are likely to be influenced substantially under anaesthesia. We implanted blood pressure ... -
Repeated anaesthesia with isoflurane and medetomidine-midazolam-fentanyl in guinea pigs and its influence on physiological parameters
Schmitz, Sabrina; Guth, Brian; Tacke, Sabine; Henke, Julia (PLoS, 2017)Repeated anaesthesia may be required in experimental protocols and in daily veterinary practice, but anaesthesia is known to alter physiological parameters in GPs (Cavia porcellus, GPs). This study investigated the effects ... -
Successful implantation of an abdominal aortic blood pressure transducer and radio-telemetry transmitter in guinea pigs: anaesthesia, analgesic management and surgical methods, and their influence on hemodynamic parameters and body temperature
Schmitz, Sabrina; Guth, Brian; Henke, Julia; Tacke, Sabine (Elsevier, 2016)Introduction Guinea pigs (GPs) are a valuable cardiovascular pharmacology model. Implantation of a radio-telemetry system into GPs is, however, challenging and has been associated with a high failure rate in the past. We ...